20 movies like Splice, ordered by similarity : The Endless(2017), Mimic(1997), The Fly(1986), The Fly(1958), Die, Monster, Die!(1965), I Am Legend(2007), Terror Birds(2016), Upgrade(2018), Only Lovers Left Alive(2013), From Beyond(1986), Daybreakers(2009), Annihilation(2018) ...
5.7/10
Sci-Fi, Horror
Canada|France|USA|Germany
2009
107 Minutes
Adrien Brody Sarah Polley Delphine Chaneac Simona Maicanescu David Hewlett Abigail Chu Brandon McGibbon Jonathan Payne
scientist creature husband wife brother boss thrilling offbeat melodramatic playful laboratory farm apartment woods barn science experiments unusual romance marriage evolution
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
6.5/10
Horror, Mystery & Thriller, Sci-Fi
USA
2017
111 Minutes
Aaron Moorhead Aaron Moorhead Justin Benson Callie Hernandez Tate Ellington Lew Temple James Jordan Shane Brady Kira Powell Emily Montague Peter Cilella
brother cult leader cult member creature camper chilling dark thrilling intense suspenseful disturbing camp woods lake compound boat forest cult mystery mythical creatures
As kids, they escaped a UFO death cult. Now, two adult brothers seek answers after an old videotape surfaces and brings them back to where they began.
6.0/10
Horror, Mystery & Thriller, Sci-Fi
USA
1997
105 Minutes
Mira Sorvino Jeremy Northam Josh Brolin Giancarlo Giannini Charles S. Dutton Alexander Goodwin Alix Koromzay F. Murray Abraham
scientist colleague husband humanoid child transit worker suspenseful frightening melodramatic new york city subway train station laboratory underground apartment epidemic science disappearance unlikely allies evolution
Three years ago, entomologist Dr. Susan Tyler genetically created an insect to kill cockroaches carrying a virulent disease. Now, the insects are out to destroy their only predator, mankind.
7.6/10
Horror, Sci-Fi
USA|UK|Canada
1986
95 Minutes
Jeff Goldblum Geena Davis John Getz Joy Boushel Leslie Carlson George Chuvalo Michael Copeman David Cronenberg Carol Lazare Shawn Hewitt
scientist girlfriend reporter editor mutant creepy tense thrilling laboratory apartment clinic teleportation experiments mutation abortion relationships failure quest love fall
A brilliant but eccentric scientist begins to transform into a giant man/fly hybrid after one of his experiments goes horribly wrong.
7.1/10
Horror, Sci-Fi
USA
1958
94 Minutes
Al Hedison Patricia Owens Vincent Price Herbert Marshall Kathleen Freeman Betty Lou Gerson Charles Herbert Eugene Borden Torben Meyer Harry Carter Charles Tannen
scientist wife brother son mutant inspector dark shocking canada laboratory household factory teleportation experiments family death housefly quest metamorphosis sacrifice
A scientist has a horrific accident when he tries to use his newly invented teleportation device.
5.6/10
Mystery & Thriller, Sci-Fi, Horror
UK
1965
78 Minutes
Boris Karloff Nick Adams Freda Jackson Suzan Farmer Terence de Marney Patrick Magee Paul Farrell Leslie Dwyer
scientist townsperson girlfriend father mother servant creepy offbeat intense estate england village mutation experiments science gone awry meteorite family transformation discovery love
A young man visits his fiancée's estate to discover that her wheelchair-bound scientist father has discovered a meteorite that emits mutating radiation rays that have turned the plants in ... See full summary »
7.2/10
Horror, Sci-Fi, Drama
USA
2007
101 Minutes
Will Smith Alice Braga Dash Mihok Charlie Tahan Salli Richardson-Whitfield Willow Smith Darrell Foster April Grace Joanna Numata Samuel Glen James McCauley
scientist survivor dog mutant biologist dark gritty tense bleak thrilling frightening new york city apartment laboratory abandoned town street safe house death survival kidnapping
Years after a plague kills most of humanity and transforms the rest into monsters, the sole survivor in New York City struggles valiantly to find a cure.
3.5/10
Sci-Fi, Horror
USA
2016
87 Minutes
Jessica Lee Keller Lindsey Sporrer Greg Evigan Leslie Easterbrook Dillon Cavitt Evan Miller Sarah Joy Byington Heath Allyn
scientist daughter father bird friend millionaire brutal suspenseful thrilling shocking spectacular intense laboratory woods ranch wilderness home aviary horror killer animals
When Maddy Stern discovers her father has gone missing during a routine birdwatching excursion, she and her college pals trek out into the wilderness to find him, only to end up in a ... See full summary »
7.5/10
Sci-Fi, Action, Horror
USA|Australia
2018
95 Minutes
Logan Marshall-Green Betty Gabriel Harrison Gilbertson Christopher Kirby Benedict Hardie Melanie Vallejo Richard Cawthorne Clayton Jacobson Sachin Joab Michael M. Foster Linda Cropper
mugger paraplegic wife murderer doctor artificial intelligence brutal dark amusing gory gripping unrestrained parking lot hospital room laboratory house office car superhuman abilities revenge
Set in the near-future, technology controls nearly all aspects of life. But when the world of Grey, a self-labeled technophobe, is turned upside down, his only hope for revenge is an experimental computer chip implant.
7.3/10
Sci-Fi, Romance, Drama, Horror, Fantasy
UK|Germany|Greece|France
2013
122 Minutes
Tilda Swinton Tom Hiddleston Anton Yelchin Mia Wasikowska John Hurt Jeffrey Wright Slimane Dazi Carter Logan Yasmine Hamdan Aurélie Thépaut
vampire musician married woman married man author sister bleak emotional melodramatic creative intense dark united states tangiers, morocco detroit house vampires relationships love depression
A depressed musician reunites with his lover. Though their romance, which has already endured several centuries, is disrupted by the arrival of her uncontrollable younger sister.
6.7/10
Horror, Sci-Fi
USA
1986
85 Minutes
Jeffrey Combs Barbara Crampton Ted Sorel Ken Foree Carolyn Purdy-Gordon Bunny Summers Bruce McGuire Del Russel Dale Wyatt Karen Christenfeld Andy Miller
apprentice scientist psychiatrist police detective creature gory frightening hedonistic laboratory mental institution parallel universe violence pleasure cannibalism sexual fantasy science gone awry torture discovery wretched excess temptation
A group of scientists have developed the Resonator, a machine which allows whoever is within range to see beyond normal perceptible reality. But when the experiment succeeds, they are immediately attacked by terrible life forms.
6.4/10
Horror, Sci-Fi
Australia|USA
2009
98 Minutes
Ethan Hawke Peter Spierig Willem Dafoe Claudia Karvan Michael Dorman Vince Colosimo Sam Neill Isabel Lucas Paul Sonkkila
vampire human scientist fugitive dark chilling bleak laboratory hideout apartment plagues science dangerous assignment survival death quest pursuit future
In the year 2019, a plague has transformed almost every human into vampires. Faced with a dwindling blood supply, the fractured dominant race plots their survival; meanwhile, a researcher works with a covert band of vamps on a way to save humankind.
6.8/10
Sci-Fi, Mystery & Thriller, Adventure
UK
2018
115 Minutes
Natalie Portman Jennifer Jason Leigh Gina Rodriguez Tessa Thompson Tuva Novotny Oscar Isaac Benedict Wong David Gyasi Sonoya Mizuno John Schwab
biologist soldier husband monster creature scientist creepy dark uneasy frightening thrilling base camp house woods forest secret location cabin creatures mutation saving the planet
A biologist signs up for a dangerous, secret expedition into a mysterious zone where the laws of nature don't apply.
4.5/10
Mystery & Thriller, Sci-Fi, Horror
Canada
2016
89 Minutes
Alanna LeVierge Nina Kiri Adam Christie Kate Fenton Michael Lipka Brooke Henderson Glen Reid Deborah Jayne Reilly Smith
bike messenger courier evil twin thrilling tense intense frightening disturbing dark hospital house accident recovery hallucinations science fiction horror metamorphosis escape 2010s
After a traumatic accident, a bike courier begins to experience blackouts and hallucinations. She soon discovers that she's being dangerously influenced and even controlled by her unborn twin.
5.8/10
Horror, Comedy
Spain|USA
2003
93 Minutes
Jeffrey Combs Jason Barry Elsa Pataky Enrique Arce Simón Andreu Santiago Segura Tommy Dean Musset Bárbara Elorrieta Ángel Plana Javier Sandoval Lolo Herrero
mad scientist prison official reporter doctor cellmate warden offbeat dark thrilling amusing prison cell laboratory death reanimating the dead experiments survival science gone awry obsession discovery
After 13 years in prison, the mad scientist from Re-Animator (1985) gets a new chance to experiment with the arrival of a young prison doctor, who secretly hopes to learn to reanimate dead people. Good intentions turn to horror.
5.4/10
Sci-Fi, Horror
USA
2006
93 Minutes
Christian Oliver Dean Stapleton Courtney Mace Jurgen Jones Thomas Buesch Philip Chidel
medical student mad scientist assistant disturbing dark cabin woods experiments death suicide identity immorality metamorphosis wretched excess 2000s
A doctor invents a resurrection formula and tests it by killing his assistant over and over and over again.
6.0/10
Horror, Mystery & Thriller
UK|Canada|USA
2015
90 Minutes
Carrie-Anne Moss Xavier Samuel Danny Huston Tony Todd Mckenna Grace Adam Nagaitis Maya Erskine Carol Anne Watts
monster husband wife mad scientist scientist frankenstein frankenstein's monster engaging shocking suspenseful sad powerful los angeles science creatures humanity life monsters discovery underdog
Told from Igor's perspective, we see the troubled young assistant's dark origins, his redemptive friendship with the young medical student Viktor Von Frankenstein, and become eyewitnesses to the emergence of how Frankenstein became the man - and the legend - we know today.
7.0/10
Horror, Animation, Sci-Fi
Japan
1989
67 Minutes
pervert girlfriend businessman office worker monster ghost frightful gory disturbing wild japan apartment office street curse experiments accidental death mutation world domination fetish
A businessman accidentally kills The Metal Fetishist, who gets his revenge by slowly turning the man into a grotesque hybrid of flesh and rusty metal.
6.0/10
Sci-Fi, Horror
UK|USA
1990
92 Minutes
Dylan McDermott Stacey Travis John Lynch William Hootkins Iggy Pop Mark Northover
android ex-soldier girlfriend artist boyfriend junk dealer emotional offbeat frightening thrilling wasteland city apartment dystopia junkyard united states robots man vs. machine post-apocalypse survival
The head of a cyborg reactivates, rebuilds itself, and goes on a violent rampage in a space marine's girlfriend's apartment.
Sci-Fi, Action, Fantasy
2010
180 Minutes
Rajnikanth Aishwarya Rai Bachchan Danny Denzongpa Santhanam Karunas
scientist fiancée android gangster police officer hilarious frenetic eerie melodramatic india laboratory mansion street car city scientific experiments artificial intelligence love triangle engagement science gone awry
Sci-Fi, Adventure, Comedy, Action, Horror, Mystery & Thriller
2013
90 Minutes
Tara Reid Ian Ziering John Heard Cassie Scerbo Jaason Simmons Alex Arleo Neil H. Berkow Heather Jocelyn Blair
man daughter ex-wife drunk police officer shark campy emotional intense los angeles house bar street truck helicopter tornado shark attack danger survival stress
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