20 movies like Sssssss, ordered by similarity : The Man With the X-Ray Eyes(1963), Altered States(1980), Dr. Cyclops(1940), The Incredible Two-Headed Transplant(1971), Species III(2004), Trail of the Screaming Forehead(2007), The Fly(1986), The Incredible Shrinking Man(1957), The War of the Worlds(1953), Upgrade(2018), Evolution(2001), Rise of the Planet of the Apes(2011) ...
Sci-Fi
1973
99 Minutes
Strother Martin Dirk Benedict Heather Menzies Richard B. Shull Tim O'Connor Jack Ging Kathleen King Reb Brown Ted Grossman Charles Seel Ray Ballard
college student mad scientist daughter doctor sheriff campy creepy college laboratory scientific experiments snakes experimental medicine physical transformation metamorphosis discovery wretched excess 1970s
A snake scientist (Strother Martin) turns his daughter's (Heather Menzies) boyfriend (Dirk Benedict), his lab helper, into a big cobra.
Sci-Fi
UK|USA
1963
79 Minutes
Ray Milland Diana Van der Vlis Harold J. Stone John Hoyt Don Rickles Morris Ankrum Lorie Summers Dick Miller Kathryn Hart Jonathan Haze John Dierkes
scientist friend colleague pastor murderer creepy dark laboratory carnival church casino science experiments alienation madness sight discovery transformation fall 1960s
A European prince terrorizes the local peasantry while using his castle as a refuge against the "Red Death" plague that stalks the land.
Sci-Fi
USA
1980
103 Minutes
William Hurt Blair Brown Bob Balaban Charles Haid Thaao Penghlis Miguel Godreau Dori Brenner Peter Brandon Charles White Eagle Drew Barrymore Megan Jeffers
scientist psychologist wife creepy intense shocking university mexico united states experiments drugs psychology marital problems discovery metamorphosis 1970s
A psycho-physiologist experiments with drugs and a sensory-deprivation tank and has visions he believes are genetic memories.
Sci-Fi
USA
1940
75 Minutes
Albert Van Dekker Janice Logan Thomas Coley Charles Halton Victor Kilian Frank Yaconelli Billy Wilkerson Allen Fox Paul Fix Frank Reicher
biologist scientist doctor mineralist professor servant chilling creepy amazon jungle laboratory house bedroom experiments biology madness murder self-sacrifice shrinking quest
A mad scientist working in the South American jungle miniaturizes his colleagues when he feels his megalomania is threatened.
Sci-Fi
USA
1971
88 Minutes
Bruce Dern Pat Priest Albert Cole John Bloom Casey Kasem Berry Kroeger Larry Vincent Jack Lester Darlene Duralia Gary Kent
mad scientist maniac boy landlord wife caretaker campy outlandish creepy offbeat countryside laboratory operating room head transplants murder personality clash madness uncontrollable experiment metamorphosis discovery
Dr. Roger Girard is a rich scientist conducting experiments on head transplantation. His caretaker has a son, Danny, who, although fully grown, has the mind of child. One day an escaped ... See full summary »
Sci-Fi
2004
111 Minutes
Sunny Mabrey Robin Dunne Robert Knepper Amelia Cooke John Paul Pitoc Natasha Henstridge Michael Warren Christopher Neame
alien beautiful girl biochemist college student daughter hunter incredible gory gripping ambulance college laboratory power plant aliens monsters mating ritual reproduction murder scientific observation metamorphosis
An alien hybrid beauty (Sunny Mabrey) follows her overwhelming, but deadly, urge to mate while commandos hunt her down.
Sci-Fi, Comedy
USA
2007
88 Minutes
Brian Howe Dan Conroy Andrew Parks Fay Masterson Alison Martin Jennifer Blaire Larry Blamire Betty Garrett Dick Miller Daniel Roebuck Susan McConnell
scientist alien priest colleague sailor townsperson creepy campy hilarious laboratory small town alien invasion research experimental medicine science gone awry mass hysteria metamorphosis escape pursuit 1950s
A small town infestation of crawling alien foreheads that begin attaching to people and taking them over collides with a scientist's experiments to extract foreheadazine and things go horribly horribly wrong.
Horror, Sci-Fi
USA|UK|Canada
1986
95 Minutes
Jeff Goldblum Geena Davis John Getz Joy Boushel Leslie Carlson George Chuvalo Michael Copeman David Cronenberg Carol Lazare Shawn Hewitt
scientist girlfriend reporter editor mutant creepy tense thrilling laboratory apartment clinic teleportation experiments mutation abortion relationships failure quest love fall
A brilliant but eccentric scientist begins to transform into a giant man/fly hybrid after one of his experiments goes horribly wrong.
Sci-Fi
USA
1957
81 Minutes
Grant Williams Randy Stuart April Kent Paul Langton William Schallert Billy Curtis Diana Darrin Helene Marshall
husband wife doctor dwarf spider cat fascinating emotional campy dark boat house doctor's office circus dollhouse basement science radiation marriage mutation
When Scott Carey begins to shrink because of exposure to a combination of radiation and insecticide, medical science is powerless to help him.
Sci-Fi
USA
1953
85 Minutes
Gene Barry Ann Robinson Les Tremayne Lewis Martin Robert Cornthwaite Sandro Giglio Bill Phipps Jack Kruschen Vernon Rich Paul Birch
scientist pastor sheriff alien marine suspenseful creepy los angeles farmhouse church laboratory alien invasion showdown survival discovery revenge 1950s
A small town in California is attacked by Martians, beginning a worldwide invasion.
Sci-Fi, Action, Horror
USA|Australia
2018
95 Minutes
Logan Marshall-Green Betty Gabriel Harrison Gilbertson Christopher Kirby Benedict Hardie Melanie Vallejo Richard Cawthorne Clayton Jacobson Sachin Joab Michael M. Foster Linda Cropper
mugger paraplegic wife murderer doctor artificial intelligence brutal dark amusing gory gripping unrestrained parking lot hospital room laboratory house office car superhuman abilities revenge
Set in the near-future, technology controls nearly all aspects of life. But when the world of Grey, a self-labeled technophobe, is turned upside down, his only hope for revenge is an experimental computer chip implant.
Sci-Fi, Comedy
USA
2001
101 Minutes
David Duchovny Orlando Jones Seann William Scott Julianne Moore Ted Levine Ethan Suplee Katharine Towne Michael Ray Bower Pat Kilbane Ty Burrell Gregory Itzin
college professor scientist firefighter geologist military officer general hysterical suspenseful cheeky melodramatic new mexico desert laboratory underground college mutation research alien landing military intervention cover-up
A fire-fighting cadet, two college professors, and a geeky but sexy government scientist work against an alien organism that has been rapidly evolving since its arrival on Earth inside a meteor.
Sci-Fi, Action, Adventure
USA|UK|Canada
2011
105 Minutes
James Franco Freida Pinto John Lithgow Brian Cox Tom Felton David Oyelowo Andy Serkis Tyler Labine Jamie Harris David Hewlett Ty Olsson
scientist father chimpanzee ceo girlfriend lab worker gripping thrilling emotional san francisco animal shelter laboratory california war genetic modification animal intelligence man vs. beast science gone awry experiments quest
A substance designed to help the brain repair itself gives advanced intelligence to a chimpanzee who leads an ape uprising.
Mystery & Thriller, Sci-Fi, Drama
USA
2018
100 Minutes
Gugu Mbatha-Raw Lorraine Toussaint Saniyya Sidney David Strathairn Christopher Denham Hannah Kauffmann Avery Akerson Levi Dylan Monique Straw Ramona King Richard L. Olsen
mother daughter grandmother cop sheriff scientist bleak brooding dreamy somber spirited desert cottage car small town family home on the run super powers apocalypse energy field
After years in hiding, a woman is forced to go on the run when her superhuman abilities are discovered. Years after having abandoned her family, the only place she has left to hide is home.
Sci-Fi, Horror
USA
2016
87 Minutes
Jessica Lee Keller Lindsey Sporrer Greg Evigan Leslie Easterbrook Dillon Cavitt Evan Miller Sarah Joy Byington Heath Allyn
scientist daughter father bird friend millionaire brutal suspenseful thrilling shocking spectacular intense laboratory woods ranch wilderness home aviary horror killer animals
When Maddy Stern discovers her father has gone missing during a routine birdwatching excursion, she and her college pals trek out into the wilderness to find him, only to end up in a ... See full summary »
Sci-Fi
USA
1960
103 Minutes
Rod Taylor Alan Young Yvette Mimieux Sebastian Cabot Tom Helmore Whit Bissell Doris Lloyd Paul Frees Bob Barran
scientist doctor morlock eloi housekeeper campy thrilling incredible england household laboratory fallout shelter museum time travel apocalypse adventure discovery future
A man's vision for a utopian society is disillusioned when travelling forward into time reveals a dark and dangerous society.
Sci-Fi, Horror
Canada|France|USA|Germany
2009
107 Minutes
Adrien Brody Sarah Polley Delphine Chaneac Simona Maicanescu David Hewlett Abigail Chu Brandon McGibbon Jonathan Payne
scientist creature husband wife brother boss thrilling offbeat melodramatic playful laboratory farm apartment woods barn science experiments unusual romance marriage evolution
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
Sci-Fi, Fantasy, Action, Adventure
China|USA
2018
112 Minutes
Tom Hardy Michelle Williams Riz Ahmed Scott Haze Reid Scott Jenny Slate Melora Walters Woody Harrelson Peggy Lu Malcolm C. Murray Sope Aluko
journalist scientist philanthropist alien goon love interest amusing brash dark thrilling unrestrained san francisco new york city shop laboratory apartment alien possession superhuman abilities fighting
A failed reporter is bonded to an alien entity, one of many symbiotes who have invaded Earth. But the being takes a liking to Earth and decides to protect it.
Mystery & Thriller, Sci-Fi, Horror
UK
1965
78 Minutes
Boris Karloff Nick Adams Freda Jackson Suzan Farmer Terence de Marney Patrick Magee Paul Farrell Leslie Dwyer
scientist townsperson girlfriend father mother servant creepy offbeat intense estate england village mutation experiments science gone awry meteorite family transformation discovery love
A young man visits his fiancée's estate to discover that her wheelchair-bound scientist father has discovered a meteorite that emits mutating radiation rays that have turned the plants in ... See full summary »
Sci-Fi, Action, Fantasy
2010
180 Minutes
Rajnikanth Aishwarya Rai Bachchan Danny Denzongpa Santhanam Karunas
scientist fiancée android gangster police officer hilarious frenetic eerie melodramatic india laboratory mansion street car city scientific experiments artificial intelligence love triangle engagement science gone awry
Horror, Mystery & Thriller, Sci-Fi
USA
1997
105 Minutes
Mira Sorvino Jeremy Northam Josh Brolin Giancarlo Giannini Charles S. Dutton Alexander Goodwin Alix Koromzay F. Murray Abraham
scientist colleague husband humanoid child transit worker suspenseful frightening melodramatic new york city subway train station laboratory underground apartment epidemic science disappearance unlikely allies evolution
Three years ago, entomologist Dr. Susan Tyler genetically created an insect to kill cockroaches carrying a virulent disease. Now, the insects are out to destroy their only predator, mankind.